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Fragile foal syndrome (FFS)

Summary

Fragile foal syndrome (FFS) is a genetic disorder found in Warmblood horses, Thoroughbreds and breeds that have included these bloodlines. FFS usually causes foetal loss. Foals that survive until birth are born with extremely fragile skin and lax limb joints. Their skin can be easily torn or damaged by normal contact with their surroundings. Foals with FFS are usually euthenized due to their inability to stand and the continual risk of severe infection from their skin injuries.

FFS is an autosomal recessive disorder. Autosomal disorders are equally likely to affect male or female horses, while "recessive" means that a horse needs to inherit the FFS mutation from both its sire and its dam to be affected.

The carrier rate for Warmbloods in Australia is slightly over 10%. Thoroughbred carriers have also been found.

Gene or region and technical reference

Gene: LH1 (causative). Reference: Patent (not patented in Australia)

Reported alleles

n. Test developed using manufactured DNA, animal controls.

FFS. Test developed using manufactured DNA, animal cases.

Panels: groups of tests that are often ordered together

This test is in the Arabian health & colour panel.


horse

This foal was born dead. Its large skin tears are due to fragile foal syndrome (FFS).

Order tests

There is a one-off sample processing fee of $40 per animal plus the cost of your tests.

How many animals are you testing? Discount or society code:


Pedigree

$33 DNA profile ... more


Panels


Colour panels

$40 Dilutions panel ... more

$120 Full colour panel ... more

$70 Patterns panel ... more


Panels by breed

$115 Arabian health & colour ... more

$50 Arabian health panel ... more

$40 Friesian health & colour ... more

$120 Gypsy health & colour ... more

$50 Miniature ACAN panel ... more

$250 Miniature health & colour ... more

$160 QH health & colour ... more

$90 QH health panel ... more


Good moves


Gaited horses

$9 Lateral gait marker ... more


Good looks


Coat colour

$9 Agouti (bay factor) (agouti) ... more

$9 Red/black ... more


Coat pattern

$9 Frame overo/lethal white syndrome (OLWS) ... more

$9 Grey/melanoma ... more

$9 Lp/Appaloosa/night blindness (CSNB) ... more

$9 PATN1 coat pattern modifier (PATN1) ... more

$9 Roan marker ... more

$9 Sabino 1 ... more

$9 Splashed white 1/deafness (SW1) ... more

$9 Splashed white 2/deafness (SW2) ... more

$9 Splashed white 3/deafness (SW3) ... more

$9 Tobiano ... more

$9 W13 dominant white (W13) ... more

$9 W20 white markings (W20) ... more

$9 W22 dominant white (W22) ... more

$9 W25 dominant white (W25) ... more

$9 W26 dominant white (W26) ... more

$9 W27 dominant white (W27) ... more


Good health


Paint horses

$9 Splashed white 3/deafness (SW3) ... more


Good looks


Colour dilution

$9 Champagne ... more

$9 Cream ... more

$9 Dun and d1 (nd1) (dun/d1) ... more

$9 Pearl ... more

$9 Taffy/silver/eye abnormalities (MCOA/silver) ... more


Good health


Multiple breeds

$14 Foal immunodeficiency syndrome (FIS) ... more

$14 Fragile foal syndrome (FFS)

$9 Frame overo/lethal white syndrome (OLWS) ... more

$9 Grey/melanoma ... more

$9 Lp/Appaloosa/night blindness (CSNB) ... more

$14 Polysaccharide storage myopathy 1 (PSSM1) ... more

$9 Splashed white 1/deafness (SW1) ... more

$9 Taffy/silver/eye abnormalities (MCOA/silver) ... more


Pure- and part-bred Akhal-Tekes

$14 Naked foal syndrome (NFS) ... more


Pure- and part-bred Arabians

$14 Cerebellar abiotrophy (CA) ... more

$14 Lavender foal syndrome (LFS) ... more

$14 Occipitoatlantoaxial malformation (OAAM) ... more

$14 Severe combined immune deficiency (SCID) ... more


Pure- and part-bred Connemaras

$14 Hoof wall separation disease (HWSD) ... more


Pure- and part-bred Friesians

$14 Friesian dwarfism ... more

$14 Hydrocephalus ... more


Pure- and part-bred Miniature horses

$14 D1 form of Miniature dwarfism (D1) ... more

$14 D2 form of Miniature dwarfism (D2) ... more

$14 D3 form of Miniature dwarfism (D3) ... more

$14 D4 form of Miniature dwarfism (D4) ... more

$140 Skeletal atavism (SA) ... more


Pure- and part-bred Quarter Horses and Paints

$14 Glycogen branching enzyme deficiency (GBED) ... more

$14 Hereditary equine regional dermal asthenia (HERDA) ... more

$14 Hyperkalaemic periodic paralysis (HYPP) ... more

$14 Immune mediated myositis (IMM) ... more

$14 Malignant hyperthermia (MH) ... more

$9 Splashed white 2/deafness (SW2) ... more


Pure- and part-bred Saddlebreds

$14 Junctional epidermolysis bullosa (JEB2) ... more

Tests can be in the list more than once when the gene in question has more than one effect. It is OK to select the same test once or more than once, the price is the same.