We are taking a summer break from December 21 to January. You can still place orders now and while we are on break. If we we receive but don't finish testing your samples before Christmas they will be at the top of our list when we re-open in January. Samples that arrive during the break will be stored carefully for testing in January.
Thanks for all the testing you've sent us this year, and have a wonderful summer!
Severe combined immune deficiency (SCID)
Summary
Severe combined immune deficiency (SCID) can appear in pure- and part-bred Arabians. Horses affected by SCID lack a functional immune system and are unable to fight infections. In their first few months foals are protected by antibodies in the mare's colostrum but as this protection declines their lack of immune system becomes apparent. The most common signs are respiratory illness, intermittent fever and/or diarrhoea. There is currently no effective treatment for SCID.
SCID is an autosomal recessive disorder. Autosomal disorders are equally likely to affect male or female horses, while "recessive" means that a horse needs to inherit the SCID mutation from both its sire and its dam to be affected.
Gene or region and technical reference
Gene: DNA-PKcs (causative). Reference: Patent (ceased)
Reported alleles
n. Test developed using animal controls.
SCID. Test developed using animal cases.
Panels: groups of tests that are often ordered together
This test is in the Arabian health & colour panel.
This test is in the Arabian health panel.