Equine DNA testing
Genetic disorders
Packages
5 panel, 6 panel (QH, Paint etc.)
Various breeds
Overo lethal white syndrome (frame overo)
Congenital stationary night blindness (appaloosa)
Polysaccharide storage myopathy type 1 (PSSM1)
Arabians, pure and part-bred
Severe combined immune deficiency (SCID)
Friesians, pure and part-bred
Warmbloods, pure and part-bred
Fell Ponies, Dale Ponies and Gypsy horses, pure and part-bred
Foal immunodeficiency syndrome (FIS)
Quarter horses and related breeds, pure and part-bred
Hyperkalemic periodic paralysis (HYPP)
Glycogen enzyme branching deficiency (GBED)
Hereditary equine regional dermal asthenia (HERDA)
Saddlebred and related breeds, pure and part-bred
Junctional epidermolysis bullosa (JEB)
Akhal Teke, pure and part-bred
Connemara, pure and part-bred
Hoof wall separation disease (HWSD)
Coat colour tests
Parentage
Us
Practical Horse Genetics
Why test for hoof wall separation disease?
Hoof wall separation disease (HWSD) is an inherited disorder that has been found in Connemara ponies. In ponies affected by HWSD the hoof wall separates from the internal structures of the foot and breaks. Without a strong hoof wall, the weight of the pony goes disproportionately through the sole of the foot. This can cause lameness. Signs of HWSD are not present at birth but usually start at less than six months of age.
HWSD is an autosomal recessive disorder. Autosomal disorders are equally likely to affect male or female horses, while "recessive" means that a horse needs to inherit the HWSD mutation from both its sire and its dam to be affected. Horses that have inherited the HWSD mutation from just one parent are called HWSD carriers, and do not have physical signs of this disorder.
Our information and terminology is based on the sequences and content in Finno et al., 2017, describing a single nucleotide insertion in the SERPINB11 gene.
HWSD
HWSD affects all four feet. In affected ponies the hoof wall separates easily from the underlying structures of the foot.
